Potentially Lethal Ventricular Arrhythmias and Heart Failure in Arrhythmogenic Right Ventricular Cardiomyopathy
What Are the Differences Between Men and Women?
AUTHORS: Yoshitaka Kimura, MD, Takashi Noda, MD, PhD, et.al.
Japanese researchers set out to evaluate gender related differences in cases of arrhythmogenic right ventricular cardiomyopathy (ARVC). This phenomenon was previously thought to occur largely in males. They found that female gender was an independent risk factor of heart failure mortality or heart transplantation. Men, on the other hand, had a greater risk of ventricular tachycardia and/or ventricular fibrillation.
The authors wrote: “… intervention in the malignant progress of ARVC itself is still a challenging issue. Our study of sporadic ARVC demonstrated a female predominance in HF-related adverse outcomes, suggesting that we should pay careful attention to this possibility when treating female ARVC patients.”
They also call for investigation of novel intervention, such as exercise restriction or load reducing therapies.