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The Fetal Rat Brain is Default Female Unless Exposed to Testosterone

May 13, 2015 / SGWHC Editorial Staff / Blog
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Brain feminization requires active repression of masculinization via DNA methylation The March 30 issue of Nature Neuroscience includes an interesting article that may help explain different reproductive behaviors of male vs. females. Researchers at the University of Maryland studied development of fetal rats and found that the developing mammalian brain is destined for a female […]

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Endocrinology, physiology, Preclinical Research, Sex Determinants

The Fetal Rat Brain is Default Female Unless Exposed to Testosterone

May 13, 2015 / SGWHC Editorial Staff / Journal Articles
1
mouse

Brain feminization requires active repression of masculinization via DNA methylation AUTHORS: Bridget M Nugent, Christopher L Wright, Amol C Shetty, Georgia E Hodes, Kathryn M Lenz, Anup Mahurkar, Scott J Russo, Scott E Devine & Margaret M McCarthy The developing mammalian brain is destined for a female phenotype unless exposed to gonadal hormones during a […]

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Endocrinology, physiology, Preclinical Research, Sex Determinants

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