Alcohol and Aldehyde Dehydrogenases Contribue to Sex-Related Differences in Clearance of Zolpidem in Rats AUTHORS: Peer, C.J., Stronge, J.D., et al Objectives: The recommended zolpidem starting dose was lowered in females (5 mg vs. 10 mg) since side effects were more frequent and severe than those of males; the mechanism underlying sex differences in pharmacokinetics […]
Alcohol Dehydrogenase, Aldehyde Dehydrogenase, Animal Studies, Pharmacology, Zolpidem
Sex bias in drug research: a call for change AUTHOR: Alyson J. McGragor In the March 2016 issue of The Pharmaceutical Journal, A Royal Pharmaceutical Publication, we again see a thoughtful article by Dr. Alyson J. McGregor, a founding board member of the Sex and Gender Women’s Health Collaborative. In the article, she makes the […]
Drug Doses, gender, Personalized Medicine, Pharmaceuticals, Pharmacology, sex, sex differences
6 reasons to be skeptical of the new “Female Viagra” There is much controversy over the August 18, 2015 FDA approval of a new drug, Filbanserin which purportedly will treat condition of “Female Hypoactive Sexual Desire Disorder, which was renamed “Female Sexual Interest/Arousal Disorder in 2013. An interesting article by Julia Bellez in Vox.com summarizes […]
female viagra, libido, Pharmacology, sexual dysfunctionA systematic review of the inclusion (or exclusion) of women in HIV research: from clinical studies of antiretrovirals and vaccines to cure strategies. AUTHORS: Curno, Mirjam J; Rossi, Samuela; Hodges-Mameletzis, Ioannis; Johnston, Rowena; Price, Matt A.; Heidari, Shirin Abstract Introduction: The effect of clinical interventions can differ due to sex/gender. Studies have shown that women […]
AIDS, Antiretroviral, HIV, immunology, infectious disease, NIH, Pharmacology, Vaccine