Are Women Appropriately and Adequately Included in Clinical Trials of Moxifloxacin? Elisa Chilet-Rosell, PhD,1 Ma Teresa Ruiz-Cantero,1,2 and Ma Angeles Pardo, MSc11Public Health Research Group, University of Alicante, Alicante, Spain.2CIBER Epidemiología y Salud Pública (CIBERESP), Spain. [email protected] ABSTRACT Purpose: To determine the inclusion of women and the sex-stratification of results in moxifloxacin Clinical Trials (CTs), […]
Clinical trials, medication, Pharmacology, prescription drugs
SS Dhruva, RF Redberg The Safety and Effectiveness of Medical Treatments can differ in men and women formany reasons related to different epidemiologic characteristics, physiology, and body size. In general, women have higher bleeding rates and procedural morbidity and mortality than men, which means that their risk/benefit ratios for many implanted medical devices can […]
Clinical trials, medical devices
In response to a review of clinical trials on drug bioequivalence, Larry Cahill , PhD, a Professor of Neurobiology and Behavior, at the University of California/Irvine, argues that the exclusive reliance on testing generic drugs in males in indefensible. Turns out “inactive” ingredients can produce very different- even opposite- reactions to the effectiveness of the […]
Clinical trials, Medications, prescription drugs
G Koren1, H Nordeng2 and S MacLeod3 1Motherisk Program, Division of Clinical Pharmacology/Toxicology, SickKids Hospital, University of Toronto, Toronto, Ontario, Canada; 2School of Pharmacy, Oslo University, Oslo, Norway; 3Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada. Correspondence: G Koren ([email protected]) Received 3 October 2012; accepted 20 November 2012; advance online publication 9 […]
Clinical trials, Medications, prescription drugs, research reporting
